Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI), a class of anti-depressants, mostly prescribed for people suffering from an obsessive-compulsive disorder. To vet proposals, he recruited a powerhouse advisory board of prominent biologists, drug developers, and clinical researchers, led by world-renowned drug researcher Robert Siliciano of Johns Hopkins. In-patient use. - Quora, Heres presentation I gave at the re-open California Conference on January 9,2021: How to fix the problemHow to fix the problem Steve Kirsch Executive DirectorCOVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008Google Docs[https://docs.google.com/presentation/d/1-A4y78wv3tTPmVu57FOabY6j-MJbPwMGojKwZfaCkAs/. But even she was drained by Kirschs constant attempts to override the data. He is frequently brash and interruptive, peppering dire warnings about vaccines with veiled aspersions toward Anthony Fauci and vague references to influential people who agree with him in private but cannot speak publicly. The group who declined the drug were very sick with 12.5% requiring hospitalization and one died. Fluvoxamine is an inexpensive drug that has been in use for 37 years and has been used by an estimated 10 million people. A very short op-ed arguing for using fluvoxamine against COVID. His appearance on an episode of anti-covid-vaccine, pro-ivermectin pundit Bret Weinsteins DarkHorse podcast, alongside Robert Malone, a prominent source of vaccine misinformation, introduced Kirsch to followers of the intellectual dark web, who have since embraced him as a fellow truth-teller. Doctors wait for government permission (EUA or added to the NIH guidelines) before using a drug. In the second trial, it was shown to be 100% effective in long-haul COVID symptoms: None of the treated patients had any long-haul symptoms after 2 weeks compared to 60% of untreated patients having 1 or more of the 15 long-haul symptoms after two weeks, and 29% having 4 of more of the long haul symptoms after 2 weeks. In other cases, stop cold turkey. He started a covid-19 vaccine company. I've collected fluvoxamine evidence here for convenient access. There is no evidence fluvoxamine is harmful and led to a worse outcome. The study was also featured on 60 Minutes. Has it really been 25 years, a whole quarter of a century? Stopping the meds will return you to your normal self. , or the patient is simply sensitive to the drug (50mg twice a day can be too much for some people). this is NOT about the science. That study was featured on 60 Minutes. But they dont want their names used. When you need to characterize me, you need to say that Steve Kirsch doesnt go with majority votes on interpreting data, he told me when I asked about his views on ivermectin, which he insists is a silver bullet against covid. Thirty minutes past the end of our scheduled time, he dropped his phone in the cupholder of his Tesla so that he could keep talking while he ran an errand. Both drugs have compelling data that is hard to explain if the drug doesn't work. Reason is the hospital gets release from liability if they follow NIH guidelines. But they will refuse to give it to you even after being proven in a Phase 3 trial that was approved by the WHO. The track management was so impressed, they asked for prescriptions. There are 4 outpatient studies that have been done (2 at WashU (see. Its not about the science. Its the gold standard of medical evidence. Skirsch.io Steve Kirsch Home page Fluvoxamine, COVID, pandemic, . Its actually much harder to parse out a signal than if youre treating diabetes or cancer., In addition to the issues with fluvoxamine, advisors grew increasingly uncomfortable with Kirschs posts about ivermectin, which he has repeatedly claimed in blog posts and appearances in alternative media can be used together with fluvoxamine to prevent 100% of covid-19 deaths. But how many did it help? Talking to Kirsch is an exhausting experience. See this Wall Street Journal op-ed. He prefers iconoclastic approaches, whether by directly funding asteroid detection or advocating for nuclear power to combat global warming. The NIH wrote a bullshit rejection because the FDA told them not to approve it. And, according to three members of CETFs scientific advisory board, he put pressure on them to promote fluvoxamine for clinical use without conclusive data that it worked for covid. Fluvoxamine (Luvox) is a Selective Serotonin Receptor Inhibitor (SSRI) that is clinically indicated for OCD in children, and can be used off label for depression. and increased heart rate (which could be nerves about the dilated pupils). Paper reviewing the evidence and mechanisms of action for fluvoxamine: Lenze Phase 2 RCT published Nov 12, 2020: Seftel RWE trial that confirmed the Phase 2 trial published Feb 1, 2021. Timing is everything with respect to outcomes. It used to be that a Phase 3 study would do it. Jan 17. Steve Kirsch Nov 5, 2021 145 92 Here are the key things you should know about fluvoxamine for COVID: It works. This drug can save your life but you have to ask for it! Compulsive fiddling with your mask? Once the Phase 2 result came out, it should have been embraced by doctors. Author Affiliations . There may be a depression of libido while on drug, but since the drug is taken on acute basis, this is only temporary and it reverses once the drug is stopped. Online Status. Doctors who have used fluvoxamine in the US and other countries swear by it. Fluvoxamine has a 40 year safety track record. . Months later, the site wont disclose how many doses it helped deliveror what it plans to do with user data. Dosing. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. Online. All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. I wanted to get the article out before my flight left. This is the gold standard of evidence based medicine, Article about the fluvoxamine rejection (The Verge). Here are my answers. Late in the session, minutes before this impromptu video wrap up, Tip o' Spear Steve Kirsch addressed the panel and revealed that the FDA had just shot down Fluvoxamine as an approved COVID treatment. David Boulware, a researcher at the University of Minnesota, received $125,000 to test the drug against covid. Pretty much nothing changed when the Phase 3 trial confirmed fluvoxamine worked. The NIH never did a risk benefit analysis of this drug. A video presentation by Steve Kirsch, Executive Director of the Covid-19 Early Treatment Fund. You will be wired for 24 hours if you dont heed my advice. In severe cases, it takes longer. May 16, 2022. All the medical journals refused to publish the meeting notes (rejected by 6 journals). The data we have today with just 2 clinical trials (RCT and confirmatory RWE) is compelling. Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. His latest startup, M10, is a spin-off of a spin-off that sells a blockchain for banks. They rejected the drug for insufficient evidence just like they always do for ivermectin. Infoseek lost out to Yahoo; it had a chance to grow bigger, but it didn't. Kirsch told me that meta-analyses are a higher level of evidence than randomized controlled trials. When I responded that meta-analyses are only as good as the data they are based on, he said Id like to understand your source on that, because I cant find a source that says a phase 3 trial is greater evidence than a meta-analysis., When you characterize me, you need to say that Steve Kirsch doesn't go with majority votes on interpreting data.. ALWAYS check with your doctor and report any medications you are taking before or plan to take after you start taking fluvoxamine. To date, the #1 drug with the most evidence to make a significant difference, without any doubt, is fluvoxamine. The results would, eventually, set Kirsch on a collision course with the scientific establishment. Di scl ai mer: T he vi ews expressed i n t hi s art i cl e are my own personal opi ni on based on my 1, 000+ hour st udy of cut t i ng edge . Vitamin D, NAC, betadine, aspirin, and Nigella sativa are all super cheap, effective, and available without a prescription. Indeed, some of the most prominent people spreading misinformation about ivermectin and vaccines today began by promoting hydroxychloroquineincluding by claiming to debunk Boulwares data analysis. just like ivermectin). There is absolutely no evidence that either one of these claims is true, as Morris has carefully documented. Always be self aware when using fluvoxamine. Ivermectin has been falsely promoted as a covid treatmentbut for those who use the drug legitimately, seeing it become a piece of anti-vaccine misinformation is disconcerting. The anecdotal data of 100% success rates is further icing on the cake. Steve Kirsch's Newsletter ^ | 02/26/22 | Steve Kirsch. Peter Meinke, another former board member, spent nearly three decades in drug discovery at Merck. $1M reward: Do we need more data re: Fluvoxamine for COVID-19? He pushes fluvoxamine, an anti-depression drug which despite doing very well in covid treatment studies has been strangely neglected. February 17, 2021. . The WashU Phase 3 study hasnt been disclosed yet, but they had compliance problems with their patients this time around (phase 2 was local so the patients got the drug early and also were very compliant and the placebo group was truly taking nothing). Fluvoxamine is the poster child of the COVID-19 Early Treatment Fund (CETF). Also, for people who cant tolerate fluvoxamine for whatever reason (nausea, jittery, etc), this is the alternative. The paramedics will think you are on drugs. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. There are two ways Ive discovered that I may be able to save the world, he told an IEEE Spectrum reporter in 2000. Steve Kirsch, current director of the Covid 19 Early Treatment fund is an MIT alumni who has made a career as a tech entrepreneur. Please, As of November 13, fluvoxamine has been proven to work in every trial that has published results, including, studies. I fully expected both organizations to do absolutely nothing. Here's why. Your best bet is to. They left their recommendation of fluvoxamine at NEUTRAL. . Kirsch said that his attempts to promote fluvoxamine are being curtailed. Fluvoxamine, Proxalutamide, and Ivermectin: 100% success I'm very bullish on two drug combos since it is rare for Read More The best COVID treatments for hospitalized patients Seven treatments for hospitalized COVID patients with very high success rates. It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. Three of the four outpatient trials have been reported out: all were successful. See the repository above. It does not matter how many lives will be saved. Fluoxetine is just as effective. more time. See more below. He retired at the largest pension in federal history. So check the side-effects list to be familiar with which side-effects are associated with which drug so if you have a side-effect, youll know which drug to reduce or eliminate. In other cases, stop cold turkey. ). Vaccine waitlist Dr. B collected data from millions. You can help by bringing this document to your doctor's attention. Mr. Steve Kirsch - A philanthropist and former Silicon Valley tech executive. Even though an expert panel was overwhelmingly convinced in just one hour, hearing a very small subset of all the supporting evidence, the organizations that they belong to are taking their time. . Get your prescription in advance of getting COVID. Patients should be advised to limit/avoid the use of caffeine while on the drug since fluvoxamine extends the half life of caffeine (making you super wired).