Blindness caused by onchocerciasis is decreasing, and there are regions of Latin America and Africa that have been shown to have eliminated the disease altogether. [15][76] Merck Sharp & Dohme remains a subsidiary of the Merck & Co. Zero tariff on importations, a favorable supply chain, and the second largest access to nickel deposits in the region puts the Philippines in the bullseye of the worlds [35], In 1965, Merck & Co. acquired Charles Frosst Ltd. of Montreal (founded 1899), creating Merck-Frosst Canada, Inc., as its Canadian subsidiary and pharmaceutical research facility. In the case below, the original source material is given along with a sample of student work. Clinical trials help find new treatments to help save and improve lives. Learn more about Merck's Environmental, Social & Governance (ESG) approach by visiting merck.com/company-overview/esg. We bring creative minds together to invent important medicines and vaccines. Biological oxygen demand has also been reduced. You can specify conditions of storing and accessing cookies in your browser. Here are the largest importers since the start of the invasion. The university then set up non-exclusive licenses with seven companies to ensure a reliable supply of the antibiotic. Compare prices to get a bargain. Inventory turnover 2009 2010 2011 2012 However, its likely no surprise that the pandemic has also been great for many healthcare businesses. It originated in Germany late in the seventeenth century with operations in the United States starting in Ranked: Visualizing the Largest Trading Partners of the U.S. In 2022, the WHO warned that we could see a shortage of up to 2 billion syringes if manufacturing cant keep up. And different populations like the elderly or children may need different preparations, he adds. From New York to Damascus, this infographic uses EIU cost of living data to rank the worlds most and least expensive cities to live in. Other mutagenic drugs that treat infectious diseases have come to market, he notes. COVID-19 has brought conventional syringe vaccines into sharp focus, with many criticizing the challenges associated with them. Buy the cheapest items no matter what. WebAbout. Merck develops and produces medicines, vaccines, biologic therapies and animal health products. [173], In response to the ruling, MSD initiated counter-litigation in the United States in January 2016 by filing a federal lawsuit which accused its former parent company of "infringing on its trademark" through actions that included the increased usage of "Merck KGaA" and "MERCK" in branding in the US as well as on its social media presence. True/False. For the annual Rankings, JUST Capital collects and analyzes corporate data to evaluate the 1,000 largest public U.S. companies across 20 Issues identified through comprehensive, ongoing public opinion research on Americans' attitudes toward responsible corporate behavior. The drug, which inhibits a polymerase enzyme used during viral replication, has been at the center of a controversy involving Ridgeback's attempt to win BARDA funding. Other major products by the company include Isentress (raltegravir), an antiretroviral medication used to treat HIV/AIDS that had $857 million in 2020 revenue; Simponi (golimumab), a human monoclonal antibody used as an immunosuppressive drug that had $838 million in 2020 revenue; RotaTeq, a rotavirus vaccine that had $797 million in 2020 revenue; and Lynparza (olaparib), a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults that generated $725 million in 2020 revenue for the company.[1]. [57] Merck's involvement is considered a key factor in the success against the disease all over the world,[147] and the decision to donate the entirety of the drug to all those in need of it is used as part of the Mectizan Donation Program that covers countries such as Yemen and African countries. Anderson RJ, Groundwater PJ, Todd A, Worsely AJ. To learn more, visit: www.JUSTCapital.com. [175], In 2021, an investigation by Reuters revealed that Merck's baldness drug Propecia caused persistent sexual dysfunction in men. %PDF-1.6 % [69][70] The CEO of Elsevier's Health Sciences Division, Michael Hansen, admitted that the practice was "unacceptable". In the United States and Canada, the company trades under the name EMD (an abbreviation of Emanuel Merck, Darmstadt), its legal name here says Merck KGaA, Darmstadt, Germany, and instead of "Merck Group", the "EMD Group" name is used. Merck ranked No. [65][66] Merck & Co. spun Medco off ten years later. We are determined to find solutions for the most serious chronic health challenges, such as cardiovascular disease and diabetes. [58][59][60], In 1982, the company formed a joint venture, KBI Inc., with AstraZeneca. [54][55], In 1979, Merck scientists developed lovastatin (Mevacor), the first drug of the statin class. The US is home to some of the largest market cap stocks in the world, including blue-chip companies in diverse sectors such as Amazon, Microsoft, Coca-Cola, Visa and Johnson & Johnson. With a market capitalization of 2.64 trillion U.S. dollars as of April 2021, Apple was the worlds largest company in 2022. Industry average 10.6 11.2 10.8 11.0 To learn more about their plans to pioneer the future of needle-free drug delivery, click this link now. Merck & Co. Inc. $90,847,000,000: Pharmaceutical Company: North America: 9. This is particularly true in the UK where there are at least 400 victims and the legal protection afforded to the victims and their families is particularly weak. Our mission is to tackle the most pressing social challenges of our time by galvanizing the collective power of corporate America. There can be no guarantees with respect to pipeline candidates that the candidates will receive the necessary regulatory approvals or that they will prove to be commercially successful. VLS-101 is currently Phase I and Phase II clinical trials. [104], In November 2019, the company acquired Calporta, which focused on Parkinsons and Alzheimers treatments. Please make a tax-deductible gift today. [155] As of mid-2008, when the plaintiff class had reached the threshold percentage required by Merck to go through with the settlement, plaintiffs had prevailed in only three of the twenty cases that had reached juries, all with relatively small awards. Merck & Co. traces its origins to its former German parent company Merck Group, which was established by the Merck family in 1668 when Friedrich Jacob Merck purchased a drug store in Darmstadt. And the immunologist believes Merck's skills and experience can accelerate the progress that other, smaller developers already have made. >>>Interested in investing in NuGen Medical Devices? Our progress is due in large part to the important and tough scientific questions we set out to answer with our trials and collaborations. [120], In April 2021, Merck acquired Pandion Therapeutics for $1.85 billion, expanding its offering in treating autoimmune diseases. [72], In November 2009, Merck & Co. completed a merger with Schering-Plough in a US$41 billion deal. [126][127][128][129], In July 2021, Merck completed the corporate spin-off of Organon & Co.[130], In September 2021, Merck announced it would acquire Acceleron Pharma for $11.5 billion, gaining control over Sotatercept, used in the treatment of pulmonary hypertension, and luspatercept-aamt. In 1891, with $200,000 received from E. Merck, Weicker started Merck & Co., with headquarters in lower Manhattan. Private Securities Litigation Reform Act of 1995. Weve been fully committed to developing an effective response to the COVID-19 pandemic since it was first recognized. [41], In 1953, Merck & Co. merged with Philadelphia-based Sharp & Dohme, Inc., becoming the largest U.S. drugmaker. . Private Securities Litigation Reform Act of 1995. Inventory 6,000 6,900 6,900 7,200 Which of the following is true for the Student Version above? Editors Note: A previous version of this graphic was missing some key companies such as GSK and AbbVie. See our latest news, announcements and multimedia resources. False, Liquidity management Bauman Companys total current assets, total current liabil- Having a market cap value of $125 billion in 2019, Eli Lilly has jumped to a current value of $214.9 billion, a significant growth of 72%. True It includes approximately 100,000 screen-ready extracts and represents approximately 60% of all known plant genera in the world. [83][84], Between 2010 and 2015, the company cut around 36,450 jobs. WebMerck has now committed more than $1 billion to expand capacity, with a focus on underserved countries. This could result in the severe disruption to routine vaccinations and promote unsafe recycling of syringes in order to administer vaccines. The agency's former director, Rick Bright, filed a whistleblower complaint that went into great detail about how his bosses allegedly pressured him to fund EIDD-2801's development, which he worried could present serious toxicities. [102], In May 2019, Merck announced it would acquire Peloton Therapeutics, developer of a HIF-2alpha inhibitor for Von HippelLindau disease-associated renal cell carcinoma, for up to $2.2 billion. [137][138], On December 7, 2012, the foundation announced that it was ending its donations to the Boy Scouts of America citing its discrimination against gay people. There will have to be a rigorous, thoughtful, data-driven process to select the most promising ones." And unlike the many COVID-19 vaccine candidates that use nonreplicating vectors or just engineered versions of the coronavirus surface protein, this approach may only need a single shot because the viruses copy themselves, potentially producing high levels of spike that elicit strong immune responses. [149][non-primary source needed] Vioxx became one of the most prescribed drugs in history. [133], Since it was founded in 1957, the Merck Company Foundation has distributed $740 million in overall charitable distributions including more than $480 million to educational and non-profit organizations. United States Department of Health and Human Services, Australasian Journal of Bone and Joint Medicine, New Jersey Business and Industry Association, American College of Obstetricians and Gynecologists, United States Environmental Protection Agency, "Merck & Co., Inc. 2022 Form 10-K Annual Report", "Merck Names 30-Year Company Veteran as CFO", "Merck Appoints Caroline Litchfield Chief Financial Officer", "Merck names Treasurer Caroline Litchfield CFO effective April 1", https://www.fiercepharma.com/special-reports/top-10-most-profitable-pharma-companies-2021, https://www.drugdiscoverytrends.com/pharma-50-the-50-largest-pharmaceutical-companies-in-the-world/, "The top 10 best-selling diabetes drugs of 2013", "Sitagliptin in the treatment of type 2 diabetes: a meta-analysis", "Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: systematic review and meta-analysis of randomised and non-randomised studies", "AHA: IMPROVE-IT Proves Ezetimibe Benefit", "Systematic review and meta-analysis of the efficacy and safety of existing TNF blocking agents in treatment of rheumatoid arthritis", "Merck and Johnson & Johnson Reach Agreement on Distribution Rights for Remicade and Simponi", "Merck, Samsung Bioepis Launch Remicade Biosimilar in U.S.", "HIGHLIGHTS OF PRESCRIBING INFORMATION: GARDASIL", "HIGHLIGHTS OF PRESCRIBING INFORMATION: ISENTRESS", "Merck Melanoma Drug Is First PD-1 Inhibitor OK'd by FDA", "HIGHLIGHTS OF PRESCRIBING INFORMATION: Keytruda", "Merck sues Taiwan company over generic antibiotic product", "LABEL: ERTAPENEM- ertapenem sodium injection", "A Pill to Treat Covid-19? Vaccines are one of the greatest public health success stories and weve been discovering, developing and delivering vaccines to help prevent disease for over 100 years. It has to constantly find new ways to customize medicines while researching and developing new tools and drugs. [168] They alleged that Merck failed to pay proper rebates to Medicaid and other health care programs and paid illegal remuneration to health care providers. FRANKFURT, March 2 (Reuters) - Germany's Merck KGaA MRCG.DEon Thursday predicted 2023 earnings would slip, warning of a decline at its electronic [47][48], Maurice Hilleman, a scientist at Merck, developed the first mumps vaccine in 1967,[49] the first rubella vaccine in 1969,[50] and the first trivalent measles, mumps, rubella (MMR vaccine) in 1971. Moreover, when the COVID-19 pandemic hit, global immunization dropped even further with 25 million children missing out on routine vaccines in 2021 alone. The New York Stock Exchange (NYSE) and Nasdaq are the top stock exchanges in the world by market capitalisation. As of August 2020, South Korea operates a fleet of 24 nuclear reactor units, representing 23.2 gigawatts (GW) of capacity, at four nuclear power complexes.In 2019, South Koreas nuclear fleet generated 139 terawatthours (TWh) of electricity, making South Korea the fifth-largest nuclear power producer in the world and accounting for 26% of With conventional needles facing so many challenges, its no surprise that investors are taking interest in viable alternatives. The U.S. Is Betting on It", "The history of heroin: From King Tut to cough remedy", "Opioid epidemic shares chilling similarities with past drug crises", "This month in 1917: A tale of two Mercks", "With Merck & Co. Offering, Goldman Sachs Emerges from the Shadow of World War I", "In another round of Merck vs. Merck, Germany-based Merck KGaA notches a win in the U.K.", "Germany's Merck KGaA Wins Battle Over Name in U.K.", "Fight over Merck name sees German firm win in British court", "Chlorothiazide. The country also captures 45% of the global market. [54] Under his leadership, the company's investment in R&D grew threefold, and Merck became the largest pharmaceutical company in the world. The case came to a head when a research scientist believed he was communicating with Merck & Co regarding a research grant in oncology, when in fact he was talking with the Merck Group. [116] The company also announced it would acquire OncoImmune for $425 million and its phase 3 candidate, CD24Fc, used in the treatment of patients with severe and critical COVID-19. [86], In July 2015, Merck and Ablynx expanded their 18-month-old immuno-oncology collaboration by four years, generating a potential $4.4 billion in milestone payments for the Abylnx. Biggest companies in the world by market value 2022. As countries work through a backlog of vaccinations to close the immunization gap that has worsened since the pandemic, demand for syringes has significantly increased. How The Weeknd climbed from indie music anonymity to being one of the world's biggest pop stars. [114][115], In November 2020, Merck announced it would acquire VelosBio for $2.75 billion, developer of VLS-101, an antibody-drug conjugate designed to target Tyrosine kinase-like orphan receptor 1 (ROR1) in both hematological and solid tumors. In 1929, H. K. Mulford Company merged with Sharp and Dohme, Inc. and brought vaccine technology, including immunization of cavalry horses in World War I and delivery of a diphtheria antitoxin to Merck & Co. Worldwide Days later the company announced it would acquire IOmet Pharma, with IOmet becoming a wholly owned subsidiary of Merck & Co. Finance The worlds 10 biggest pharmaceutical companies 3) Immune Design Corp", "Princeton University and The Merck Company Foundation Announce Creation Of New Global Health Scholars Program and Lecture Series", "Boy Scouts of America: Merck pulls funding in protest at gay ban", "Merck to Create New Patient Assistance Program for Vaccines", "Patient Assistance Available Prescription Assistance Programs From Merck & Co.", "Merck JV plans to show up J&J, Sanofi with low-cost cholera vaccine", "Merck & Co & UNICEF USA's Partnership to Save and Protect Children", Onchocerciasis: Africa's victory over river blindness, "Shocker! [80], In August 2014, Merck acquired Idenix Pharmaceuticals for $3.85 billion. Prior to the settlement, Merck had prevailed in 3 of 5 so-called bellwether trials. We examine how nations and the scientific community have responded to the conflict, Charted: Teslas Unrivaled Profit Margins, Ranked: The Top Online Music Services in the U.S. by Monthly Users, Super-Sized Bets for Footballs Big Game (2013-2022). Routine vaccination saves millions of lives every single year, according to the World Health Organization (WHO). 8) IDENIX PHARMACEUTICALS, INC. IMPERIAL BLUE CORPORATION", "Merck & Co., Inc. Financials SEC Filings SEC Filings Details", "SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. [140] Merck & Co. offers seven patient assistance programs, each with specific eligibility requirements. Perlmutter agrees that "ordinarily you prefer not to advance a mutagen," but he says the drug, which can be given as a pill, has been "well tolerated" in the U.K. trial and that they plan to look closely at its cancer-causing potential in reproductive and developmental biology animal studies. By embracing disruptive technologies like 3D printed drugs, artificial intelligence guided therapies, and preventive medicine while working with regulatory agencies, the pharmaceutical companies will benefit from having a digital revolution. https://www.merck.com/wp-content/uploads/sites/5/2020/02/oncology.jpeg, Environmental, Social & Governance (ESG) Report. [91], In July 2016, the company acquired Afferent Pharmaceuticals, developer of a candidate used to block P2RX3 receptors, for approximately $1 billion, plus up to $750 million in milestone payments. Item On Wednesday, Eli Lilly, one of the world's biggest pharmaceutical companies, announced it was slashing the price of its most widely prescribed insulin by Guided by the priorities of the public, our research, rankings, indexes, and data-driven tools help deliver on the promise of stakeholder capitalism and an economy that works for all Americans. We'd like to develop a linear function that models their sales as a function of time. [125], In July 2021, Robert M. Davis became CEO, succeeding Kenneth Frazier, who became executive chairman. [42][43][44][45][46][25] The combined company kept the trade name Merck in the United States and Canada, and as Merck Sharp & Dohme (MSD) outside North America. [71], In 2005, CEO Raymond Gilmartin retired following Merck's voluntary worldwide withdrawal of Vioxx. The 2023 figure was given as 1.55 trillion yuan ($224 billion). Merck now plans to develop a VSV-based COVID-19 vaccine in partnership with the International AIDS Vaccine Initiative (IAVI), a nonprofit that was originally set up to push forward HIV vaccines but has broadened its portfolio to include vaccines for a wide range of other diseases. RAHWAY, NJ / ACCESSWIRE / January 13, 2023 / Merck (NYSE:MRK), known as MSD outside of the United States and Canada, was named one of America's Most JUST Companies, making this the sixth consecutive year that Merck has been recognized for its commitment to serving its workers, customers, communities, the environment, and shareholders. Brianna Holt and Kim Renfro. [94], In April 2017, Merck Animal Health acquired Valle S.A., a Brazilian animal health product manufacturer. time series for these measures of liquidity. In 2020, the company had 6 blockbuster drugs or products, each with over $1 billion in revenue: Keytruda (pembrolizumab), a humanized antibody used in cancer immunotherapy that had $14.3 billion in 2020 revenue; Januvia (sitagliptin), an anti-diabetic medication used to treat type 2 diabetes that had $5.3 billion in 2020 revenue; Gardasil, an HPV vaccine that had $3.9 billion in 2020 revenue; Varivax, a varicella vaccine used to protect against chickenpox that had $1.9 billion in 2020 revenues; Bridion (Sugammadex), a neuromuscular-blocking drug that had $1.2 billion in 2020 revenue; and Pneumovax 23, a pneumococcal polysaccharide vaccine that had $1.1 billion in 2020 revenue. 10. 1 in the pharmaceuticals and biotech industry for the third straight year, notably also ranking as the top company for communities and customers in the industry. [citation needed], In 1985, Merck received approval for imipenem, the first member of the carbapenem class of antibiotics. According to the World Health Organization's latest table of COVID-19 vaccines, 124 candidates are at various stages of development with eight different technologies, or platforms. [88], In January 2016, Merck announced two new partnerships; the first with Quartet Medicine and its small molecule pain treatments,[89] the second with Complix investigating intracellular cancer targets,[90] with both collaborations potentially generating up to $595 million and $280 million respectively. Additional factors that could cause results to differ materially from those described in the forward-looking statements can be found in the company's Annual Report on Form 10-K for the year ended December 31, 2021 and the company's other filings with the Securities and Exchange Commission (SEC) available at the SEC's Internet site (www.sec.gov). [154] In November 2007, Merck agreed to pay $4.85 billion to settle most of the pending Vioxx lawsuits. That vaccine uses an engineered vesicular stomatitis virus (VSV) to shuttle a gene for the Ebola virus surface protein into a host's cells. [112], In August 2020, Merck Animal Health acquired IdentiGEN, engaged in DNA-based animal traceability. [77], In October 2013, Merck announced it would cut 8,500 jobs in an attempt to cut $2.5 billion from its costs by 2015. Despite being the leading COVID-19 vaccine manufacturer in North America, Pfizer slid in the rankings to third place. [172] Merck of Darmstadt has initiated litigation against its former subsidiary, Merck & Co. (MSD) of Kenilworth, in several countries over infringing use of the Merck name. [179], Merck was a Conference Supporter for the Virtual ISPOR Asia Pacific conference in September 2020. [160], Fosamax (alendronate) is a bisphosphonate used for the treatment of post-menopausal osteoporosis and for the prevention of skeletal problems in certain cancers. In 2015 the Merck Group adopted a new logo and said it will be "much more aggressive" about protecting the brand of "the real Merck". Brianna Holt and Kim Renfro. One of the COVID-19 vaccine candidates that Merck decided to back aims to build off the success it had with an Ebola vaccine that came to market last year. Its also virtually painless and leaves no mark on the skin. WebMerck Animal Health is one of the worlds largest producers of vaccines for animals, producing over 102 billion doses per year. 2009 2010 2011 2012 Were following the science to tackle some of the worlds greatest health threats. [144][non-primary source needed], In 1987, Merck began a program with UNICEF to donate its new drug Mectizan to "all that need it for as long as needed"[145] in an effort to combat onchocerciasis, also known as river blindness, primarily in Africa. [56], Merck scientist William C. Campbell and Satoshi mura developed ivermectin for veterinary use in 1981, and later put it to human use against Onchocerciasis in 198788 with the name Mectizan;[57] today the compound is used against river blindness, lymphatic filariasis, scabies and other parasitic infections. We follow the science where we can make the greatest difference, now and in the future. parent. "When you start thinking about immunizing billions of people, the idea of having to track people down for boosters is very problematic," Perlmutter says. The company this morning announced it has cut deals to develop and manufacture two different COVID-19 vaccines and a much-discussed experimental antiviral compound that is already in early clinical trials. How Does the COVID Delta Variant Compare? But JUST Capital is an independent nonprofit dedicated to measuring and improving corporate stakeholder performance - from fair wages to workforce diversity to climate commitments - at America's largest public companies. The company develops medicines, vaccines, biologic therapies and animal health products. Merck & Co. closed this facility in July 2010 but remerged in 2011 as Merck Canada. The primary manufacturer for the most recognizable drugs on the market pulled in a revenue of over $48 billion in 2020, a 3% increase compared to 2019. In 1996 Merck paid $1.8 million for polluting the air. [161][162][163] Long-term treatment with bisphosponates produces anti-fracture and bone mineral density effects that persist for 35 years after an initial 35 years of treatment. Merck At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. What is the impact of war on science and academia? The largest international airport in France, Charles de Gaulle, is one of the busiest airports in Europe with 76 million people flying in and out annually. To start, here are the top five biggest pharmaceutical companies in the world at the moment by market capitalization: The pharmaceutical and consumer goods giant is worth $428.7 billion inmarket cap. 212 0 obj <> endobj [36][37] Although Merck's agreement with Rutgers gave it exclusive rights to streptomycin, at Waksman's request the company renegotiated the agreement, returning the rights to the university in exchange for a royalty. On the therapy front, Merck has chosen to back development of EIDD-2801, a compound designed to inhibit diverse viruses that use RNA as their genetic material, which includes SARS-CoV-2. Subscribe to News from Science for full access to breaking news and analysis on research and science policy. Contact Info:Spokesperson: Merck & Co., Inc.Website: https://www.3blmedia.com/profiles/merck-co-incEmail: [emailprotected], View source version on accesswire.com: https://www.accesswire.com/735215/Merck-Named-One-of-Americas-Most-JUST-Companies-by-JUST-Capital-and-CNBC-Industry-Leader-in-Pharmaceuticals-and-Biotech, https://www.accesswire.com/735215/Merck-Named-One-of-Americas-Most-JUST-Companies-by-JUST-Capital-and-CNBC-Industry-Leader-in-Pharmaceuticals-and-Biotech, China to guard against risks in property market - Premier Li, UPDATE 1-China to guard against risks in property market - Premier Li, UPDATE 1-Ukrainian pilot pair in Arizona to fly military simulators -US officials, Nations secure U.N. global high seas biodiversity pact, UPDATE 1-China stresses need for tech reliance, firms should lead innovation. 27 Likes, 0 Comments - B A T H H O U S E (@bathhousesoap) on Instagram: One of the most overlooked products in the skin-care world, but has the Consumption of Fuel and Materials per Capita, Visualizing Chinas Dominance in Battery Manufacturing (2022-2027P), Mapped: The Population of Indias States Compared with Countries. WebAt Merck, we're following the science to tackle some of the world's greatest health threats. JUST Capital publishes the annual list of America's Most JUST Companies, the JUST 100, in partnership with CNBC. NuGens needle-free devices use a simple spring-loaded mechanism which uses pressure to release the liquid drug and penetrate the skin. Buy items at the check-out lane, even if they are not on your list. A settlement with Johnson & Johnson was reached in 2011, in which Merck agreed to pay $500 million. In 191 of 193 countries, the original Merck company, the Merck Group of Darmstadt, owns the rights to the "Merck" name. Our vaccines safeguard animal health and Why? [106], In January 2020, Merck acquired ArQule, developer of ARQ 531, an oral Bruton's tyrosine kinase (BTK) inhibitor, for $2.7 billion. Find out how we're supporting the future of our business and the well-being of patients, people and communities around the world. The company is ranked 71st on the 2022 Fortune 500[7] and 87th on the 2022 Forbes Global 2000,[8] both based on 2021 revenues. [103], In June 2019, Merck announced it would acquire Tilos Therapeutics for up to $773 million. JUST Capital has engaged more than 160,000 participants, on a fully representative basis, since 2015. Use your credit card, even if you don't know your balance. View additional multimedia and more ESG storytelling from Merck & Co., Inc. on 3blmedia.com. Vioxx was designed as a selective inhibitor of the enzyme cyclooxygenase-2. Comment on the firms liquidity over the 20092010 period. Ink $4B+ Expansion of Immuno-Oncology Collaboration", "Merck signs a $605M deal to bulk up in cancer immunotherapy", "Quartet, Merck Partner on Pain Treatments in Up-to-$595M Alliance", "Merck & Co. Launches Up-to-$280M Cancer Collaboration with Complix", "Merck & Co. Acquires Cancer Immunotherapy Developer IOmet", "Acquisitions, Divestitures, Research Collaborations and License Agreements", "Merck & Co. to Acquire Afferent Pharmaceuticals for Up to $1.25B", "Merck looks for a return on its Lynparza investment", "Merck Animal Health Completes Acquisition of Valle S.A.", "Merck to Acquire Rigontec, Expanding Cancer Immunotherapy Franchise", "Merck to Acquire Rigontec, RIG-I Therapeutics Pioneer, Advancing Leadership in Immuno-Oncology", "Merck & Co. completes Viralytics acquisition", "FDA Accepts Merck's Biologics License Application (BLA) and Grants Priority Review for V920, the Company's Investigational Vaccine for Ebola Zaire Virus", "Merck to buy immunotherapy developer Immune Design for $300 million", "Merck Completes Tender Offer to Acquire Immune Design", "Merck Completes Acquisition of Antelliq Corporation to Become Leader in Emerging Digital Technology for Livestock and Companion Animals", "Peloton Therapeutics' $2.2 billion deal with Merck took root with an idea for clinical trials", "Merck to buy Tilos Therapeutics for up to $773 million", "COI Pharmaceuticals Announces Acquisition of Calporta by Merck", "Merck Animal Health Completes Acquisition of Vaki to Further Broaden Its Leadership Position in Aquaculture to Advance Fish Health and Welfare", "Merck to buy Austrian vaccine maker as it jumps into COVID-19 race", "Merck Animal Health Completes Acquisition of Quantified Ag", "Merck Animal Health Completes Acquisition of IdentiGEN", "Merck to buy $1 billion stake in Seattle Genetics, co-develop cancer therapy", "Merck to buy $1 bln stake in Seattle Genetics, co-develop cancer therapy", "Merck Snaps up VelosBio and its ROR1 Inhibitor in $2.75 Billion Deal", "Merck adds experimental COVID-19 therapy with OncoImmune deal", "Merck Bolsters COVID-19 Pipeline with OncoImmune Acquisition", "Merck Animal Health Completes Acquisition of Poultry Sense Limited", "Strengthening Global Systems to Prevent and Respond to High-Consequence Biological Threats", "Merck Completes Acquisition of Pandion Therapeutics", "Merck to buy drug developer Pandion Therapeutics for $1.85 billion", "Merck Snaps up Autoimmune-Focused Pandion in Massive $1.85 Billion Deal", "Merck signs $1.2 billion deal with US government for experimental COVID treatment", "Merck says its new Covid pill reduces the risk of hospitalization, death by half for some patients", "Merck's new CEO Robert Davis begins, after Ken Frazier's retirement", "Kenneth Frazier stepping down as Merck CEO, becomes executive chairman", "Merck's Ken Frazier, one of just 4 Black CEOs in the Fortune 500, is stepping down", "Merck Announces Completion of Organon & Co. Spinoff", "Merck builds out cancer drug pipeline with Kelun-Biotech deal", "SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.